Sermorelin Acetate ODT
Product Overview
Sermorelin is a synthetic peptide that serves as an analog of Growth Hormone-Releasing Hormone (GHRH), a naturally occurring neurohormone produced in the hypothalamus.[1][2][3][4]
Sermorelin is comprised of the first 29 amino acids of GHRH, making it a potential agent for stimulating growth hormone (GH) secretion from the anterior pituitary gland.[2][3]
This mechanism has implications for assisting with growth hormone deficiencies (GHD) in both children and adults.[2]
Growth Hormone Deficiency (GHD)
Sermorelin may assist in stimulating endogenous GH production in children with GHD and adults with GH insufficiency.[2]
Emerging Potential in Hypogonadism
A study in short children suggested sermorelin may help increase not only GH, but also prolactin, FSH, and LH. The study observed small acute changes in these hormones after sermorelin administration.[2]
In rats, a study suggested sermorelin administration may lead to an increase in testosterone production. However, trials in humans have not shown significant changes in testosterone levels.[2]
Anti-Aging and Metabolic Health
Natural GH levels decline with age. Low levels of growth hormone may contribute to age-related changes such as reduced lean body mass, increased adiposity, diminished bone density, and thin dry skin.[5]
Sleep Regulation
An animal study suggested acute replacement of GHRH may positively influence sleep patterns by potentially increasing slow-wave sleep (SWS), or “deep sleep”.[6]
503A vs 503B
- 503A pharmacies compound products for specific patients whose prescriptions are sent by their healthcare provider.
- 503B outsourcing facilities compound products on a larger scale (bulk amounts) for healthcare providers to have on hand and administer to patients in their offices.
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